SAM tools
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Manage SAM files with this software. SSAM (Sequence Alignment/Map) format is a generic format for storing large nucleotide sequence alignments. SAM aims to be a format that:
1. Is flexible enough to store all the alignment information generated by various alignment programs;
2. Is simple enough to be easily generated by alignment programs or converted from existing alignment formats;
3. Is compact in file size;
4. Allows most of operations on the alignment to work on a stream without loading the whole alignment into memory;
5. Allows the file to be indexed by genomic position to efficiently retrieve all reads aligning to a locus.
SAM Tools provide various utilities for manipulating alignments in the SAM format, including sorting, merging, indexing and generating alignments in a per-position format.
The license of this software is Free, you can free download and free use this cad software.