Genome analysis made easy. This program is designed to find the optimal trees for multiple genome rearrangement by signed reversals. The problem is modeled as: For a given collection of genomes represented by signed permutations on genes, find a tree to connect the given genomes by reversal paths such that the number of all signed reversals is minimized.

The license of this software is Freeware, you can free download and free use this calculator software.