SITES is a computer program for the analysis of comparative DNA sequence data. Basic analyses include: data summaries by polymorphism class; polymorphism estimates within and between groups (species); estimates of migration, neutral model, and recombination parameters; and linkage disequilibrium analyses. SITES is primarily intended for data sets with multiple closely related sequences. It is especially useful when multiple sequences have been obtained from each of one or several closely related populations or species.

SITES can handle large data sets, and is flexible with regard to the input data. With a few commands on the command line, or in response to menus, one can tailor a particular data set in different ways to suit different questions, including working on only a subset of the data and regrouping the data.

The license of this software is Freeware, you can free download and free use this calculator software.