Analyze ECAT files with this tool. imgcbv help you with the subtraction of the contribution of vascular radioactivity from dynamic PET image in ECAT format.
Vascular volume fraction Vb can be given as a value that is common to all image pixels, or as (smoothed) Vb image, calculated from a [O-15]CO study.

Parameters:
1) Dynamic image file (corrected for decay)
2) Blood TAC file (times in minutes)
3) Vb value or Vb image file (fraction, not percentage)
4) Output image file

Options:
-h, --help
Print this message and exit
-N
Negative TAC values are preserved; by default those are set to 0
-P
Equation Ct=Cpet-Vb*Cb is applied; this is the default mode
-T
Equation Ct=(Cpet-Vb*Cb)/(1-Vb) is applied
-BL=<Output filename for blood TAC>
If datafile for blood TAC interpolated to PET frame times is needed
--version or --build
Print software build information and exit
--silent
Program works silently, printing only warnings and error messages
--verbose
Program prints lots of information about what it is doing.

The license of this software is Freeware, you can free download and free use this calculator software.