imgki
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Estimate influx constant fast and easy. imgki help you with the estimation of influx constant (Ki) from dynamic PET images in ECAT 6.3 or 7.2 format applying multiple time graphical analysis (MTGA) approach of Gjedde and Patlak and Blasberg for irreversible tracer uptake. Simple non-iterative perpendicular line fitting algorithm is applied.
Parameters:
1) Input file (Plasma or Reference region TAC; times in minutes)
2) Dynamic image file
3) Linear fit start time in minutes (0 for automatic determination)
4) Parametric image file
Options:
-Ca=<value>
Concentration of native substrate in arterial plasma (mM), e.g. glucose in [18F]FDG studies. With this option the metabolic rate (umol/(min*100 g)) is calculated.
-LC=<value>
Lumped Constant; default is 0.52. This or default LC is used in calculation of metabolic rate.
-density=<value>
Tissue density; default is 1.04 g/ml. This or default density is used only in calculation of metabolic rate.
-thr=<threshold%>
Pixels with AUC less than (threshold/100 x max AUC) are set to zero. Default is 0 %.
-max=<Max value>
Upper limit for Ki values.
-filter
Remove parametric pixel values that are over 4x higher than their closest neighbours.
-end=<Fit end time (min)>
Never use data after fit end time.
-v=<filename>
Y axis intercepts are written as an image in specified file.
-n=<filename>
Numbers of selected plot data points are written as an image.
-h or --help
Print this message and exit.
-v, --version or --build
Print software build information and exit.
--silent
Program works silently, printing only error and warning messages.
The license of this software is Freeware, you can free download and free use this calculator software.