Distribution volume estimation made easy. imglhdv help you with the estimation of distribution volume (DV) from dynamic PET images in ECAT 6.3 or 7.x format applying Lawson-Hanson non-negative least squares (NNLS) to solve general linear least squares functions. DV is estimated directly without division from one- or two-tissue compartment model.

Parameters:
1) Plasma file (times in minutes!)
2) Dynamic image file
3) Parametric image file

e.g.: imglhdv ua2918ap.kbq ua2918dy1.v ua2918dv.v

Options for model selection:
-A Automatic selection of model for separate pixels
-1 Force one-tissue compartment model for all pixels
-2 Force two-tissue compartment model for all pixels
-0 Akaike weighted average of 1- and 2-tissue compartment model results [5,6] (default)
-M Selected model is written as second 'frame' in the parametric image.

Other command line options:
-T=<threshold%>
Pixels with AUC less than (threshold/100 x plasma AUC) are set to zero. default is 0%
-E=<Fit end time (min)>
Use data from 0 to end time; by default, model is fitted to all frames.
-h or --help
Print this message and exit
-v, --version or --build
Print software build information and exit
--silent
Program works silently, printing only error and warning messages.

The license of this software is Freeware, you can free download and free use this calculator software.